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    VDRL Carbon Antigen 5ml with Controls

    Rapid Labs VDRL Carbon Antigen kit is used in a non-treponemal test for the qualitative and semi-quantitative detection of syphilis using serum (heated or unheated) or plasma.

    Syphilis is a chronic venereal infection caused by the spirochaete micro-organism Treponema pallidum. As the organism cannot be cultured on artificial media, diagnosis of syphilis depends on the detection of specific antibodies by serological tests in combination with clinical findings.

    The VDRL test is “non-treponemal” in that the antibodies detected are not specific for T. pallidum, although their presence in patient’s serum or plasma is strongly associated with infection by the organism.  This test measures antibody (IgG and IgM) produced in response to lipoidal material released from damaged host cells as well as to lipoprotein-like material released from the spirochaetes.  These antibodies tend to disappear after successful treatment of the infection.

    Rapid Labs VDRL Carbon Antigen consists of modified VDRL antigen containing microparticulate carbon, which aggregates in the presence of reagin type antibodies in serum or plasma, indicating a positive result.  The aggregation can be read macroscopically.  Non-reactive samples typically appear as a smooth non-aggregated pattern, which may form buttons in the centre of the test area.

    For professional in vitro diagnostic use only.

    Pack size – 5ml with 2 x 1ml controls