virusPHIX+

Description

SARS-CoV-2 inactivation in 10 minutes

A recent study from the Roslin Institute in Edinburgh, UK concluded that virusPHIX+™ inactivates SARS-CoV-2 in as little as 10 minutes when treated at a 1:1 sample to reagent ratio at room temperature. Under these conditions, a 10log6 reduction in SARS-CoV-2 virus titre was recorded.

1 month stabilisation of SARS-CoV-2 at room temperature

Independent study by Qnostics UK demonstrated that virusPHIX+™ stabilises SARS-CoV-2 virus RNA for at least 33 days at 20°C. Sputum samples spiked with SARS-CoV-2 RNA were analysed over 33 days, and the Ct value was compared with virusPHIX+™ treated samples and control (no stabiliser added).

Data kindly provided by Qnostics, UK.

Public Health England Inactivation Studies with SARS-Cov-2

Triplicate samples of tissue culture fluid containing 5 %%(v/ foetal calf serum, spiked with SARS CoV 2 were treated with virus PHIX ™ for indicated contact time/s or mock treated in triplicate with an equivalent volume of PBS Purified samples were immediately titrated on Vero E 6 cells to establish virus titre Reduction in virus titre following treatment is given as the difference between the mean log 10 TCID 50 /ml for treated conditions and the PBS control (Test 1). In parallel, purified samples were seeded onto Vero E6 monolayers to amplify any remaining virus over the course of up to four serial passages This test is qualitative and reports either the presence or absence of virus amplification (Test 2):